miR-15b, 126, -139,-142, -186,-191, -342, -374a, -409, -660,
-942, -1290 |
Circulating miRNAs (blood) correlating to lung function
parameters in children |
N.D. |
56 |
miR-16, -30d, -296 |
Circulating miRNAs (blood) correlating to
bronchial hyperresponsiveness |
N.D. |
57 |
miR-146a, -206, -720 |
Circulating miRNAs (blood) used in
combination as potential asthma prediction markers |
N.D. |
58 |
miR-16, -125b, -133b, -206, -299 |
Plasma miRNAs able to
distinguish asthmatics from healthy individuals or those with allergic
rhinitis |
N.D |
48 |
let-7a, miR-21, -133a, -155, -328, -1248 |
Decreased in exhaled
breath condensates from asthmatic compared to healthy subjects |
N.D |
68 |
miR-21 |
Dysregulated in circulation and lungs in allergic
experimental murine models and human allergic asthmatics, |
N.D |
9-11 |
miR-155 |
Downregulated in the lymphocytes of allergic
asthmatics during pollen season |
N.D |
172 |
miR-19a
|
Increased in airway T cells
Reduction in smooth muscle cells leads to enhanced remodeling
|
PTEN, A20
|
57,59
|
miR-221 |
Decreased levels in epithelial and sputum was
associated with eosinophilic airway inflammation in asthma |
N.D. |
61 |
miR-185 |
Identified in circulating eosinophils as a
distinguisher between healthy and asthmatic subjects. A potential
predictor of asthma severity in blood sera. |
N.D. |
62 |
miR-16 |
Negatively correlates to lung function parameters |
ADRB2 |
66 |
miR-223, -513a and -625 |
Downregulated in the blood of dust
mite allergic asthmatics compared to healthy individuals |
CBL,
PPARGC1B, ESR1 |
55 |
let-7a |
Abundant in the lungs and regulates IL-13 expression |
IL-13 |
69 |
miR-1248 |
Interacts with the 3’UTR to promote IL-5 expression |
IL-5 |
70 |
miR-15a |
Low levels in CD4+ T cells in pediatric asthma
subject |
VEGF |
71 |
miR-146a |
Downregulated in bronchial brushing samples of
asthma patients, inhibits IL-8 and CXCL1 expression and neutrophil
migration |
IRAK1 |
148 |