miRNA Function Targets# References
let-7 Major regulatory mechanism for modulation IL-13 secretion and thereby type-2 inflammation JAK1/STAT3 , IL-13, SOCS4 50, 135;50,169
miR-206 Regulator of the VEGF pathway S100A7A 48
VEGF
miR-338-3p Inhibitor of Wnt/β-catenin signaling and inducer of epithelial-mesenchymal transition WNT/ β -Catentin 48
miR-329 Unknown TGF-β1 48
miR-26a modulation of TGF-β-dependent signalling pathways and repression of inflammatory responses by promoting regulatory T cell responses or through NF-κB inhibition SMAD2, SMAD3 48
miR-7 Unknown CMKLR1 49
miR-498 Suppressing Th17 cell differentiation via STAT3 STAT3 48,50
miR-187 Regulation of T cell response via CD276 CD276 49,50
miR-143 Regulates memory T cell differentiation TGF-β1 49,50
miR-886 Regulates TGF pathway via SMAD3 SMAD3, FoxO1 49,50
miR-224 Regulates TGF pathway via SMAD4 SMAD4 49,50
miR-155 Important role in host defense, modulates IL-13 pathway in macrophages determining the M2 phenotype IL13Ra1
51,52,170,171
miR-205 Activation of ERK17 pathway MICAL2 50
miR-572 Regulates type-1 cytokine expression SOCS1 53
miR-1228 Regulates type 2 responses PPAR 53
miR-483 Inhibition of TGFβ1 TGFβ1 53
miR-1908 Inhibition of TGFβ1 SMAD2, SMAD3
MMP2 53
miR-126 Counter-regulation of IL4 effect VEGF, IRS1 53
miR-92a Regulation of IL4 effect WNT5a 53
miR-125a Dampens down TLR pathway via IL10, suppresses A20 TLR, A20 53
miR-19a Activates TGFβ signaling TGFβ1 53
miR-106a Regulation of authophagic activity NOD1/2 53
miR-181c Down-regulates Osteopontin, modulating TGF Osteopontin 53
miR18a Regulating TGF pathway CTGF 48