Results:
A total of 2,579 patients were included. There were 2,166 mild (84.0%), 144 moderate (5.6%), and 269 severe-to-critical (10.4%) patients, respectively. The flow chart of the study is available in figure 1. The demographic, epidemiological and clinical outcomes of patients are available in Table 1. The following ethnicities were represented: Caucasia (89.1%), South America (5.1%), North Africa (2.0%), Black Africa (1.2%) or other (2.6%). There were 1,630 women (63.2%). The mean age was 44.4±16.7 years old. The severe-to-critical patients were older (71.7±13.7) than the moderate (63.9±18.5) and mild (39.6±12.0; p=0.001) patients. The ratio female/male of mild, moderate and severe-to-critical patients were 2/1, 1/1 and 1.1/1.6, respectively (p<0.05).
The most prevalent comorbidities were hypertension (16.0%), diabetes (5.9%), gastroesophageal disorders (i.e. reflux and gastric ulcer) (5.0%) and heart disorders (4.9%). Moderate and severe-to-critical COVID-19 patients had higher prevalence of hypertension (60.5versus 7.9), diabetes (27.6 versus 1.9), gastroesophageal disorders (8.52 versus 4.0), renal (12.1 versus 0.5), respiratory (14.0 versus 0.5), heart (16.0 versus 1.8), liver (4.4 versus 0.8) and neurological disorders (13.7versus 0.6) than mild patients (p<0.05).