Benralizumab Benralizumab Benralizumab Mepolizumab Mepolizumab Mepolizumab
Contractile tone to histamine at: EC50 EC70 EC90 EC50 EC70 EC90
Benralizumab or mepolizumab Emax (mg/100mg bronchial tissue) -116.05±13.60 -111.90±13.28 -134.14±14.93 -101.06±29.91 -104.33±29.93 -108.29±32.16
Benralizumab or mepolizumab pIC50 8.24±0.16 ** 8.13±0.12 * 7.94±0.19 * 7.41±0.18 7.44±0.17 7.28±0.19