Study 3. Effect of benralizumab and mepolizumab on the FRC to EFS
FRCs to EFS1-50Hz were generated in isolated airways. Each EFS was delivered after that the contractile response induced by the previous EFS was terminated, usually in 3-5 min. Experiments were performed in C- and C+ tissues, and in passively sensitized airways that were incubated overnight with different concentrations of either benralizumab or mepolizumab during the sensitizing procedure.