Correlations between elevated serum levels of PRX5 and PRX6 and clinical variables in patients
Table 2 shows possible associations between significantly elevated serum levels of PRX5 and PRX6 and clinical parameters in patients with MS and NMOSD. In MS patients, no significant correlation was observed between serum PRX5 and PRX6 levels and clinical variables (CSF cell counts, CSF protein levels, Qalb, EDSS scores, duration of disease, or oligoclonal band positivity). Among NMOSD patients, serum PRX5 levels correlated positively with disease duration (rs = 0.7198, p = 0.0189); and serum PRX6 levels correlated positively with CSF protein levels (rs = 0.6727, p = 0.0330), Qalb (rs = 0.6727, p = 0.0330), and the duration of disease (rs = 0.6748, p = 0.0323). Significant correlations between serum PRX5 and PRX6 levels were confirmed in patients with NMOSD (rs = 0.7047, p = 0.0229) but not MS patients (rs = 0.5924, p = 0.0711).