GRADE framework
Twenty-five (29.1%) of the CPGs reported using the GRADE framework for the quality of evidence assessment. However, most of the CPGs combined GRADE with others grading systems; only five GPGs used the GRADE framework exclusively. Regarding the GRADE adherence: None of the included CPGs reported the explicit statement of each PICO element, only one (4%) reported SoF tables and none reported the explicit reference to all GRADE domains.